Texas A&M Institute for Genome Sciences & Society
Our facility is dedicated to driving innovation and collaboration, empowering researchers to explore the fundamental mechanisms of life, health, and disease. Our staff are experienced in nearly any genomics, multi-omics, single cell, bioinformatics and pre-clinical technology needed for modern research. With a comprehensive suite of advanced genomic and phenotyping tools, we support breakthroughs in personalized medicine, precision agriculture, evolutionary biology, and other fields that rely on deep genomic insights and phenotypic characterization. As a trusted partner, we offer tailored solutions to meet the unique needs of our clients. Our team of experts is committed to providing exceptional support, ensuring access to cutting-edge technologies, robust data analysis, and comprehensive training.
Our Cores
TIGSS consists of three core service areas, designed to support your research and provide access to state-of-the-art instrumentation, all managed by our expert research staff. Each area has a fee-for-service core that can be used independently or in combination with another of our cores. To better assist our users, TIGSS requires a consultation with our staff for the core(s) you intend to use. Below is an overview of the services offered to help guide your decision. If using multiple cores, only one consultation submission form is necessary.
We employ small animal models to identify the most effective assays for quantifying phenotypic traits and behaviors. Additionally, we offer access to the Collaborative Cross, a unique mouse genetic reference population, which facilitates research into the genetic underpinnings of health, disease, and environmental responses.
We provide a comprehensive range of services, including sample preparation, library preparation, and sequencing, available for both small and large-scale projects. In addition, we offer a collaborative workspace equipped with advanced tools, allowing researchers to access a multitude of equipment that can accelerate research and enhance productivity.
We provide a wide-array of services that include start-to-finish sequencing data analysis to custom pipeline and software development. Our bioinformaticians have decades of experience with backgrounds in metagenomics, differential gene expression, single cell, epigenetics, spatial analyses, cancer biology, plant biochemistry, protein structure prediction, comparative genomics, and much more.
aDVENTITIOUS Agent Testing
Adventitious Agent (AA) testing is the technique used to assay for contaminating agents (e.g., bacteria, viruses, fungi) that are unintentionally introduced during the manufacturing of biotherapeutics and vaccines. While most agents are benign, some can be harmful and even deadly. At TIGSS, we use Next-generation sequencing (NGS) to multiplex multiple samples for a single sequencing run, accommodating up to 600+ samples at a time. An NGS-based approach can identify novel adventitious agents, where traditional methods have historically failed.
Schedule a Drop off
Our institute operates during regular business hours, Monday through Friday from 8 AM to 5 PM, and is closed on TAMU holidays. However, we request that you coordinate a time with one of our staff members to drop off your samples as we can be in meetings, seminars, and other events. Though these situations are occasional, scheduling a sample drop off time allows us to best serve you and your research needs.
Let us know how we’re doing
We value your thoughts and opinions! Your feedback helps us continue to improve and provide the best service possible. Whether it’s a suggestion, a compliment, or constructive criticism, we appreciate you taking the time to share your experience. Your input makes a difference, and we’re grateful for your support!
News
Revvity Demo for Cellometer
Wednesday June 18,2025 at 9AM in REYN 407Join us for Revvity demoing their Cellometer, which performs cell counting with dual fluorescence and can process up to 8 samples at a time. We will run demos as long as there are samples to run. No RSVP necessary. Please email genome_core@tamu.edu to let us know if you have samples to run.
PacBio Sequencing Grant
Deadline to apply is May 30,2025 at 5PMPacBio is offering a sequencing grant to promote HiFi sequencing on the Revio Long-Read Sequencing Platform.
Eligibility: Open to all TAMU researchers working with the Molecular Genomics Core
Award: The winning project will be awarded credit equivalent to the consumable cost of one library prep and one Revio SMRT cell. Up to five runner-up projects will be awarded a 20% discount on consumables needed for a single SMRT cell pilot project.
Format: Each applicant must submit a 100-word abstract describing their sample of interest, experiment goals, and project timeline.
Deadline: All abstracts must be submitted by May 30,2025 at 5PM CDT. All discounts apply to consumables ordered by Jun 23,2025. Awarded projects will be contacted within two weeks of the submission deadline. The winner will have the opportunity to present their data at a future PacBio event.
One-Stop scRNA-seq Sequencing and Analysis
TPPC, MGC, and TBC have teamed up to provide a comprehensive scRNA-seq sequencing and analysis service on the 10x Genomics platform. This collaboration allows for the identification of cell population states and accelerates research at an unprecedented pace. Contact us today to schedule histological preparation, library preparation, sequencing, and data analysis.
TPPC Inhalation Chamber Completion
The TSE whole-body inhalation chamber offers an ideal platform for simulating human exposure to air pollutants, from acute toxicity to long-term exposure across various developmental stages. This system has significant potential for research on exposure to a wide range of toxicants, including gases such as 1,3-butadiene, ozone, chlorine, phosgene, sulfur dioxide, hydrogen sulfide, nitrogen dioxide, and ammonia. It is also suitable for studying volatile organic compounds (VOCs) like benzene, chloroform, formaldehyde, d-Limonene, toluene, acetone, ethanol (ethyl alcohol), 2-propanol (isopropyl alcohol), and hexanal.
By adding an aerosol generator to this state-of-the-art system, its capabilities will be greatly enhanced, making the TAMU toxicology community even more competitive for substantial new funding. The aerosol function will allow for the use of a broad range of environmental toxicants, including, but not limited to, ultrafine particulate matter (UPM), diesel exhaust, chlorinated compounds, metals (lead, zinc, manganese), pesticides, and per- and polyfluoroalkyl substances (PFAS).