MOLECULAR GENOMIC SERVICES

Sample/Library Preparation

Description: Our expert team employs cutting-edge techniques and state-of-the-art equipment to ensure the highest quality and accuracy in the preparation of your samples. We understand that each sample is unique, and our protocols are designed to accommodate a wide range of sample types, including DNA, RNA, and even challenging samples such as low-input or degraded specimens.

Location: Reynolds Medical Sciences Building (REYN), Room 472 206 Olsen Boulevard College Station, TX 77843

Illumina MiSeq Platform

Description: The Illumina MiSeq platform is a powerful and versatile next-generation sequencing (NGS) system that brings high-throughput sequencing capabilities within reach for a wide range of applications. Designed to deliver accurate and reliable results, the MiSeq platform offers exceptional data quality, flexibility, and ease of use. The flexibility of the MiSeq platform extends to its wide range of compatible sequencing applications. Whether you’re interested in DNA sequencing, RNA sequencing, targeted resequencing, metagenomics, amplicon sequencing, or other custom workflows, the MiSeq system offers the versatility to meet your specific research needs.

Location: Reynolds Medical Sciences Building (REYN), Room 472 206 Olsen Boulevard College Station, TX 77843

Illumina NextSeq 2000 Platform

Description: The NextSeq 2000 platform combines Illumina’s cutting-edge sequencing-by-synthesis (SBS) chemistry with innovative imaging and detection systems, enabling the parallel sequencing of millions of DNA fragments in a single run. This powerful technology provides researchers with highly accurate and reliable sequencing data, allowing for precise variant detection, gene expression analysis, and other downstream applications. Furthermore, the NextSeq 200 platform offers seamless integration with Illumina’s extensive library preparation solutions. Researchers can easily prepare their samples using a variety of library construction protocols, such as DNA-seq, RNA-seq, ChIP-seq, and targeted enrichment, ensuring compatibility and efficiency throughout the workflow.

Location: Reynolds Medical Sciences Building (REYN), Room 472 206 Olsen Boulevard College Station, TX 77843

Illumina NovaSeq 6000 Platform (NTGC)

NTGC Partnerhsip: We offer sample/library prep for sequencing on the Illumina NovaSeq 6000 platform through our partners at the North Texas Genome Center. For more details please email Genome_Core@tamu.edu.

Description: The Illumina NovaSeq 6000 is a high-end sequencer designed to provide some of the highest throughput in the market. It has the capacity to run up to two flow cells at a time, with 2 flow cell options to choose from. The highest throughput (S2) can process up to 3.3 billion reads and generate up to 1000 Gb of data (with 150 bp read lengths). The system is compatible with Illumina library preparation kits and can support virtually any sequencing application- whole genome sequencing, whole transcriptomes, whole exomes, metagenomics, and more.

Location: Science & Engineering Innovation & Research Building (SEIR) North Texas Genome Center, University of Texas at Arlington.

Oxford Nanopore GridION Platform

Description: The Oxford Nanopore GridION platform represents a revolutionary approach to next-generation sequencing (NGS), offering real-time, long-read sequencing capabilities with unparalleled flexibility and portability. Powered by nanopore sequencing technology, the GridION platform enables researchers to explore the intricacies of the genome in a highly versatile and accessible manner. The GridION platform offers several key advantages. First and foremost, it provides long-read sequencing capabilities, enabling the sequencing of DNA fragments several kilobases in length. This capability is especially valuable for applications such as de novo genome assembly, structural variant detection, and characterizing complex genomic regions.

Location: Reynolds Medical Sciences Building (REYN), Room 472 206 Olsen Boulevard College Station, TX 77843

10x Genomics Chromium Platform

Description: The Chromium platform offers a wide range of applications, including single-cell RNA sequencing (scRNA-seq), single-cell immune profiling, genome sequencing, and spatial transcriptomics. By capturing the genetic information from individual cells or regions of tissue, researchers can explore gene expression profiles, cell types, clonality, immune repertoires, and spatial relationships within tissues, all with exceptional accuracy and resolution. One of the key advantages of the Chromium platform is its ability to generate linked-reads, which provide long-range genomic information from short DNA fragments. This capability enables the detection of structural variants, haplotyping, and phasing, facilitating the study of complex genomic rearrangements and genetic variations.

Location: Reynolds Medical Sciences Building (REYN), Room 472 206 Olsen Boulevard College Station, TX 77843

10x Genomics Visum CytAssist Platform

Description: The Visium CytAssist platform is a cutting-edge solution that combines the power of spatial transcriptomics with single-cell RNA sequencing (scRNA-seq) technologies, providing researchers with a comprehensive understanding of gene expression patterns within complex tissue samples. This innovative platform revolutionizes spatial genomics studies, enabling the investigation of cellular interactions and molecular signatures in their anatomical context. At the core of the Visium CytAssist platform is the integration of Visium spatial gene expression technology with the capabilities of the 10x Genomics Chromium platform. This integration allows for the simultaneous capture of spatial and single-cell transcriptomic information, providing a holistic view of the cellular composition, gene expression profiles, and spatial relationships within a tissue sample.

Location: Reynolds Medical Sciences Building (REYN), Room 472 206 Olsen Boulevard College Station, TX 77843